Now in the church that was at Antioch there were certain prophets and teachers: Barnabas, Simeon who was called Niger, Lucius of Cyrene, Manaen who had been brought up with Herod the tetrarch, and Saul. 2 As they ministered to the Lord and fasted, the Holy Spirit said, “Now separate to Me Barnabas and Saul for the work to which I have called them.” 3 Then, having fasted and prayed, and laid hands on them, they sent them away. — Acts 13:1-3.
Through a team of prophets and preachers, the Holy Spirit separates Barnabas and Saul from the team of teachers for special missionary work. The church fasts, prays, and lays hands on Barnabas and Saul as a means of identification with their work. [Source: Bible Panorama.]